Research Experience
Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
Postdoctoral research fellow: Bashaw Lab, September 2015-present
-
Investigating conserved molecular mechanisms and regulation of axon guidance in the developing mouse spinal cord and in the drosophila embryonic nerve cord.
University of Hyderabad, India
Graduate Researcher: Sepuri Lab, 2010-2015
-
Investigated the mechanism of tRNA mediated regulation of apoptosis.
-
Investigated the mechanistic and functional details of tRNA import into mitochondria.
Awards and Fellowships
2020 DST-INSPIRE Faculty Fellowship
2018 Best Poster Presentation Award, CSHL Axon guidance Meet, New York, USA.
2012 Gold Medal in Master’s program, SV University, Tirupati, India
2012 Best Poster Presentation Award in RNA Meet, IISC, Bangalore, India
2011-2014 Senior Research Fellowship, CSIR-India
2009-2011 Junior Research Fellowship, CSIR-India
Areas of interest:
My research interests involve understanding the mechanistic details of proteostasis and axon guidance in neuronal health and disease. I’m particularly interested in how protein aggregates are cleared by proteosomal and autophagy pathways. In addition, I would like to explore the novel functional links and associated mechanisms during neural circuit assembly. My work as a graduate student provided mechanistic insights into how tRNA negatively regulates Cytochrome C mediated apoptosis and also how tRNA imports into mitochondria, while my postdoctoral research work provided molecular details of how neurons find their correct way across the midline using mouse and fly genetics combined with advanced biochemical and imaging
methods. Currently, as a DST-INSPIRE Faculty fellow, I’m interested in understanding how protein aggregates are cleared in neurodegenerative disease and how neurons coordinate the signals to guide the axons in space and time by combining my expertise in cell biology and developmental neurobiology.
|
